Our company collaborates with several universities to conduct a phase II investigator-initiated clinical trial of RS8001 (pyridoxamine) for the treatment of patients with premenstrual syndrome with psychiatric symptoms/premenstrual dysphoric disorder, with a support from the Cyclic Innovation for Clinical Empowerment (CiCLE) project of the Japan Agency for Medical Research and Development (AMED) since December 2019. CiCLE has decided to continue supporting our clinical trial.