Feb.2000
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Founded Renascience Inc. as an academic bio-venture company in Kanagawa, Japan |
Oct.2016
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License agreement with Eirion Therapeutics, Inc., USA for dermatological indications |
Dec.2019
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Adopted as an AMED’s Cyclic Innovation for Clinical Empowerment (CiCLE) program(Project for premenstrual syndrome/premenstrual dysphoric mood disorder) |
Dec.2019
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Concluded an option agreement with ASKA Pharmaceutical Co., Ltd. for a license agreement of pyridoxamine on premenstrual syndrome / premenstrual dysphoric mood disorder |
Jul.2020
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Signed an agreement with CHEST M.I., Inc. for the joint development and commercialization of respiratory AI solutions |
Dec.2020
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Initiated a PhaseⅡ investigator-initiated clinical study on premenstrual syndrome/premenstrual dysphoric mood disorder |
Dec.2020
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Option agreement with Daiichi Sankyo Co., Ltd. for the treatment of respiratory diseases including COVID-19 pneumonia and other lung injuries |
May.2021
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Collaboration agreement with Nipro Corporation for the development of chronic dialysis support system using artificial intelligence (AI) |
May.2021
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Selected as AMED Translational Research Program, seeds C (Malignant melanoma project) |
Jul.2021
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Initiated a PhaseⅡ investigator-initiated clinical study on malignant melanoma |
Sep.2021
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Listed on the Tokyo Stock Exchange Mothers market (current Growth market, securities code: 4889) |
Jan.2022
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Open Tohoku University Renascience Open Innovation Labo (TREx) |
Mar.2022
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Adopted as a sharing organization in an AMED’s Research program for Practical Application of Innovative Cancer Medicine (CML project) |
Apr.2022
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Adopted as an AMED’s Commercialization Promotion Project for Medical-engineering Collaboration (Support for small and medium-sized enterprises development and commercialization) |
Jun.2022
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Transitions from a Company with Corporate Auditors to a Company with an Audit Committee, and Introduction of Executive Officer System |
Aug.2022
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Initiation of dosing in a PhaseⅢ study of chronic myeloid leukemia |
Sep.2022
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Collaboration Agreement with HI-LEX Corporation and its Subsidiary HI-LEX Medical |
Nov.2022
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Memorandum of Understanding with NEC Solution Innovators, Ltd. |
Dec.2022
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Regulatory Approval of Ultrafine Disposable Endoscope |
Feb.2023
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Adoption of AMED Research on Development of New Medical Devices (AI Project Supporting Chronic Dialysis System) |
Mar.2023
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Adoption in AMED Practical Research Program for Intractable Diseases (Systemic Scleroderma Project) |
Apr.2023
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Results of Placebo-Controlled, Double-Blind, PhaseⅡ Investigator-Initiated Clinical Trial of RS5614, a PAI-1 Inhibitor, for Novel Coronavirus (SARS-CoV-2) Pneumonia |
Apr.2023
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Open Hiroshima University Renascience Open Innovation Labo (HiREx) |
Jun.2023
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Collaboration Agreement with Kyoto University and Daiichi Sankyo Company, Limited |
Jun.2023
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Comprehensive Collaboration Agreement with NEC Corporation on AI projects |
Aug.2023
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PAI-1 Inhibitor RS5614 Met Primary Endpoint in Phase II Investigator-Initiated Clinical Trial for Unresectable Malignant Melanoma Refractory to Nivolmab |
Aug.2023
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Achievement of Enrollment Goal in Phase II Investigator-Initiated Clinical Trial of RS8001 (pyridoxamine) for the Treatment of Patients with Psychiatric Symptoms of Premenstrual Syndrome/Premenstrual Dysphoric Disorder |
Sep.2023
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Initiation of Phase II Study for Non-Small Cell Lung Cancer |
Oct.2023
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Initiation of Phase II study for interstitial lung disease associated with systemic scleroderma |
Oct.2023
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Initiation of Phase II Study for Cutaneous Angiosarcoma |
Dec.2023
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Conclusion of Collaboration Agreement with Toray Medical Co., Ltd |
Mar.2024
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Participation in the Program on Open Innovation Platform with Enterprises, Research Institute and Academia (OPERA) of Japan Science and Technology Agency (JST) |
Mar.2024
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Conclusion of Collaboration Agreement with Nipro Corporation |
May.2024
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License agreement with HI-LEX Medical for Ultrafine Endoscope |
Jun.2024
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Signed a joint research agreement with Luxana Biotech Co., Ltd. |
Aug.2024
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Taipei Medical University (TMU) signs joint development agreement with Biotech (Taiwan) for programmable medical devices |
Sep.2024
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Rare disease drug designation for malignant melanoma treatment drug |